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HelpTest Code AMAG Antimitochondrial Antibodies, IgG
Useful For
Antimitochondrial M2 (AMA-M2) antibody testing is highly specific and useful for diagnosing Primary Biliary Cholangitis (PBC), a chronic autoimmune liver disease formerly known as primary biliary cirrhosis. It helps confirm PBC in patients with high liver enzymes, identifies the disease in symptomatic patients (fatigue/itching), and can suggest risk in asymptomatic individuals.
Specimen Requirements
Collection Container/Tube:
Preferred: Serum
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 2mL preferred, 1.5mL minimum
Collection Instructions: Centrifuge within 2 hours and aliquot serum into a plastic vial.
Specimen Stability
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) |
7 days |
| Frozen | 90 days |
Avoid multple freeze/thaw cycles.
Panel Components
Antimitochondrial Antibodies, IgG, Serum
Reference Values
<7 U/mL=Negative
7-10 U/mL=Equivical
>10 U/mL=Positive
Method
FLUOROENZYMEIMMUNOASSAY
CPT
83516
Performing Laboratory
MaineGeneral Medical Center