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Test Code CCD Cross Reactive Carbohydrate Determinant 

Important Note

See Resources Section for Interpretation Guide

Useful For

Allergen Information

MUXF3 is a cross-reactive carbohydrate structure present in a glycopeptide isolated from the glycoprotein bromelain from pineapple stem. It represents CCDs found across the plant kingdom and in insect venoms (Kamath 2023).

Clinical relevance

The clinical relevance of MUXF3 is considered negligible as no significant allergic responses associated with IgE to this epitope alone have been observed (Altmann 2007, Mari 2008, Amoah 2013).

Cross-reactivity

MUXF3 IgE has been shown to exhibit cross-reactivity with several plant-derived aeroallergens, food allergens, and allergens from venom and latex. 

Specimen Requirements

Collection Container/Tube:

Preferred: Serum

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 2mL preferred, 1.5mL minimum 

Collection Instructions: Centrifuge within 2 hours and aliquot serum into a plastic vial.

Specimen Stability

Specimen Type Temperature Time
Serum Refrigerated (preferred)

7 days

  Frozen  90 days

Reference Values

< 0.10 kUa/l = Negative

Please see Interpretation Guide for additional information.

Method

ImmunoCAP® Fluorescence Enzyme Immunoassay (FEIA)

CPT

86008

Performing Laboratory

MaineGeneral Medical Center