Test Code CCD Cross Reactive Carbohydrate Determinant
Useful For
Allergen Information
MUXF3 is a cross-reactive carbohydrate structure present in a glycopeptide isolated from the glycoprotein bromelain from pineapple stem. It represents CCDs found across the plant kingdom and in insect venoms (Kamath 2023).
Clinical relevance
The clinical relevance of MUXF3 is considered negligible as no significant allergic responses associated with IgE to this epitope alone have been observed (Altmann 2007, Mari 2008, Amoah 2013).
Cross-reactivity
MUXF3 IgE has been shown to exhibit cross-reactivity with several plant-derived aeroallergens, food allergens, and allergens from venom and latex.
Specimen Requirements
Collection Container/Tube:
Preferred: Serum
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 2mL preferred, 1.5mL minimum
Collection Instructions: Centrifuge within 2 hours and aliquot serum into a plastic vial.
Specimen Stability
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) |
7 days |
| Frozen | 90 days |
Reference Values
< 0.10 kUa/l = Negative
Please see Interpretation Guide for additional information.
Method
ImmunoCAP® Fluorescence Enzyme Immunoassay (FEIA)
CPT
86008
Performing Laboratory
MaineGeneral Medical Center