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HelpTest Code ENAPL Connective Tissue ENA Panel
Useful For
This test is a highly sensitive, automated immunoassay used to screen for IgG autoantibodies, serving as a vital aid in diagnosing Connective Tissue Diseases (CTDs).
Specimen Requirements
Collection Container/Tube:
Preferred: Serum (Gold top)
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 2mL preferred, 1.5mL minimum
Collection Instructions: Centrifuge within 2 hours and aliquot serum into a plastic vial.
Specimen Stability
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) |
14 days |
| Frozen | for longer storage |
Panel Components
| ENAPL | Connective Tissue ENA Panel |
| SMIGG | Smith (Sm) Antibodies, IgG, Serum |
| RNP | RNP Antibodies, IgG, Serum |
| SCL70 | Scl70 Antibodies, IgG, Serum |
| JO1 | Jo-1 Antibodies, IgG, Serum |
| CENP | Centromere Antibodies, IgG, Serum |
| SSAIGG | SS-A/Ro Antibodies, IgG, Serum |
| SSBIGG | SS-B/La Antibodies, IgG |
Reference Values
SMIGG, SCL70, JO1, CENP, SSAIGG, SSBIGG:
<7 U/mL=Negative
7-10 U/mL=Equivical
>10 U/mL=Positive
RNP:
<5 U/mL=Negative
5-10 U/mL=Equivical
>10 U/mL=Positive
Method
ImmunoCAP® Fluorescence Enzyme Immunoassay (FEIA)
CPT
86235x7
Performing Laboratory
MaineGeneral Medical Center