Test Code HBEE Honey Bee w/ Reflex Allergen
Useful For
Establishing a diagnosis of an allergy to honeybee, paper wasp, yellow jacket, yellow hornet, and white-faced hornet venoms
Defining the allergen responsible for eliciting signs and symptoms
Identifying allergens:
-Responsible for allergic response or anaphylactic episode
-To confirm sensitization prior to beginning immunotherapy
-To investigate the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens
This test is not useful for patients previously treated with immunotherapy to determine if residual clinical sensitivity exists, or in patients in whom the medical management does not depend upon identification of allergen specificity.
Specimen Requirements
Collection Container/Tube:
Preferred: Serum
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 2mL preferred, 1.5mL minimum
Collection Instructions: Centrifuge within 2 hours and aliquot serum into a plastic vial.
Specimen Stability
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) |
7 days |
| Frozen | 90 days |
Panel Components and Reflexes
| HBEE | Honey Bee IgE w/Rflx | Whole Allergen Honey Bee, IgE with Reflex to Components |
| HBEEM1 | Phospholipase A2 | Honey Bee Component, Phospholipase A2, Api m 1 |
| HBEEM3 | Hyaluronidase Api m2 | Honey Bee Component, Hyaluronidase, Api m 2 |
| HBEEM4 | Acid Phosphatase | Honey Bee Component, Acid phosphatase, Api m 3 |
| HBEEM5 | Dipeptidyl peptidase | Honey Bee Component, Dipeptidyl peptidase, Api m 5 |
| HBEM10 | Icarapin | Honey Bee Component, Icarapin, Api m 10 |
Reference Values
< 0.10 kUa/l = Negative
Please see Interpretation Guide for additional information.
Method
ImmunoCAP® Fluorescence Enzyme Immunoassay (FEIA)
CPT
86003x1
83520
86008x5 (if appropriate)
Performing Laboratory
MaineGeneral Medical Center
Day(s) Performed
Monday - Friday