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Test Code TACRO (FK506) Tacrolimus (FK506,PROGRAF), Blood

Performing Laboratory

NorDx Laboratories

Specimen Requirements

Draw blood in a lavender-top (EDTA) tube, and send 4.5 mL (minimum volume: 0.3 mL) of EDTA whole blood refrigerated. DO NOT CENTRIFUGE. Send in original VACUTAINER®.

Reference Values

Therapeutic Ranges:
≤3 months post renal transplant: 12.0-15.0 ng/mL
>3 months post renal transplant: 8.0-12.0 ng/mL

Potentially Toxic: 15.1-20.0 ng/mL
Toxic: >20.0 ng/mL

Methodology

Roche Cobas® E assay for Tacrolimus testing

Test Classification and CPT Coding

80197  

Day(s) Test Set Up

Monday through Sunday (Must be received by noon for same day results.)

Useful For

Providing measurement of the drug in whole blood to guide dosage adjustments for optimal immunosuppression while minimizing toxicity.